MORE WATER INDUSTRY FEATURES

• Loveland Takes Guesswork Out Of LCR Requirements

  The City of Loveland’s Water Utility has served customers for decades, proudly bringing water “from snowy caps to Loveland taps.” When the Lead and Copper Rule went into effect in the early 1990s, it was labor-intensive to find a pool of people in the correct tier to complete the sampling.

• Water Utility OT vs. IT — It’s Not A Battle, It’s A Balance

  The chemistry of optimizing water/wastewater treatment extends far beyond chlorine and oxygen. It also involves synthesizing productive insights from the flood of IT data generated by operational technology (OT) sensors, instruments, and control systems. Here’s how better operational intelligence strategies are helping IT and OT personnel collaborate to make processes more cost-efficient.

• Assess The Purity Of Your Cell Therapy Product With Confidence

  The analysis of particle contaminants in cell therapy products is critical for ensuring drug purity and safety. However, the successful characterization of such particulates requires gaining morphological insights into each type of particle present. A technique called micro-flow imaging (MFI) enables the visualization of particulate matter by providing relevant morphological details for further study of each type of particle identified. In this study, MFI was used to distinguish between NK cells and its expansion component, Cloudz™ microspheres, in different environments.

• Water Quotes From Women

  As many of my followers know, I have been writing about the connection between women and water for a long time. Here is an excerpt from a post I wrote a number of years ago, A Valentine to Women Who Keep the Water Flowing…

• Water Quotes From Famous People

  In my last post, Water Quotes from Movies and Films, and during our Water We Talking About? podcast with Paul O’Callaghan, I give a big thanks to actor Matt Damon for his efforts around water. In the hopeful documentary Brave Blue World, Matt expresses my sentiments and those of many of my fellow water professionals… "How lucky are we that we are the ones who get to solve this?"

• A Strong Track Record Of Innovative Iron And Manganese Treatment

  For many utilities, properly treating the iron and manganese in source water is critical to maintaining good customer relationships. When iron and manganese are present, they are often accompanied by arsenic contamination. Here are several examples of utilities that successfully installed treatment systems to address the trio of contaminants.

• $0 CAPEX Model Aids Innovation In Changing Water Environments

  Managers of industrial, municipal, and agricultural water quality or water use monitoring can attest to the challenges of balancing depth of detail against the costs of achieving it. Now, an Infrastructure-as-a-Service (IaaS) business model is rewriting the economic impacts of those challenges by repackaging water monitoring capabilities to meet evolving needs more efficiently.

• PFAS: The Real Cost Of Inaction

  ALTRA Proven Solutions experts believe that there are two key areas where they can have a positive impact in helping to eliminate PFAS from our environment: Advocacy and Innovation through ALTRA PFAS solutions.

• UF/RO System Treating Mine-Influenced Water To Remove Selenium

  A Phosphorus mine in Wyoming needed to treat high selenium concentrations leaching into the surface water. A 3-month pilot study of a UF/RO system was conducted to reduce selenium levels under the US EPA's maximum contaminant level (MCL) of 0.05 mg/L, and mitigate impact to the ecosystem, especially aquatic species. Read the full case study to learn how Toray's high-rejection energy-efficient RO (TMGD series) removed the selenium at reduced feed pressures, projected to save the plant energy costs for years.

• The Effect Of Rocking Rate And Angle On T Cell Cultures Grown In Expansion Systems

  Ensuring optimal and maximal T cell production is critical for adoptive immunotherapy and its continued success. The Xuri Cell Expansion System is an important component of the clinical manufacturing process so we sought to investigate the effect of the rocking rate and angle on the expansion of T cells.

• Simple Western Analysis Of Adeno-Associated Virus (AAV) Proteins For Cell And Gene Therapy

  Western blotting is notoriously challenging; it’s labor-intensive, suffers from poor reproducibility, and is only semi-quantitative. For this reason, the Cell and Gene Therapy Catapult (CGTC), an independent center of excellence at the forefront of technology and innovation for cell and gene therapy commercialization, is adopting next generation technologies to advance quality control (QC) of AAV-mediated gene therapy. In this application note, you’ll see how CGTC has used highly-specific antibodies exclusively manufactured by PROGEN with fully automated Simple Western™ assays on Wes™ to monitor and characterize AAV capsids during product purification.

• Protein Thermal Shift Assays Made Easy

  Protein thermal shift assays enable quick and easy buffer optimization for increased protein stability. Learn more about the CFX Real-Time PCR Detection Systems which uses a simple protocol to measure protein thermal stability using SYPRO Orange Fluorescent Dye.

• How To Support A Utility’s Asset Management Plan – 6 Challenges You Can Solve Now

  Helping water and wastewater utilities develop and effectively prioritize asset management plans.

• Five Steps To Great Results Using One-Step Mulitplex RT-qPCR

  One-step multiplex RT-qPCR is a technique used to rapidly quantify multiple targets directly from RNA in a single reaction. This blog explains the proper optimization and validation for successful one-step multiplex RT-qPCR as well as tips for choosing the right reagents for your needs.

• Intensified And Improved Fed-Batch Production Process: High-Density N-1 Perfusion

  The method described here allows you to intensify your fed-batch process through reduced production duration without affecting the growth or titer profile.

• ANDA Or 505(B)(2): Choosing The Right Abbreviated Approval Pathway For Your Drug

  For developers seeking to obtain approval for previously approved drug products in the United States, the U.S. Food and Drug Administration (FDA) offers two abbreviated approval pathways — an abbreviated new drug application (ANDA) and a 505(b)(2) application. Read about these in the available blog.

• MSP Marketing: Move Beyond Word of Mouth

  We’re talking marketing this spring, and there’s a really good reason for that. Business as usual is now business unusual, and when we come out of the pandemic and all the economic and social fallout, you still want to be in business. In fact, now you can see the value of not just scraping by every month – you need to be built to last. The only way to make sure you’re built to last is to master marketing. Deep down you know this – no matter how good your service is, if nobody knows about it, you don’t make money. So let’s talk first about word of mouth, because for some MSPs, it’s the only tool in their marketing toolbox. But even for the best MSPs, it’s one of the most important.

• The Role Of Ozone In Cost-Effective Reuse Treatment

  Both direct and indirect potable reuse have massive potential to address growing water scarcity issues. However, the total cost of ownership can present a significant challenge to getting reuse projects off the ground. The good news is that another solution now provides a comparable option for reuse that is often superior to common reuse treatment trains currently in operation.