MORE WATER INDUSTRY FEATURES

• “Known Unknowns” Affect Critical Process Parameters & Critical Quality Attributes In The Bioproduction Cycle

  While it’s well and good to track the known Critical Quality Attributes (CQAs), this industry needs to do a better job to diminish the impact of “unknown” outputs i.e., through stringent process control over “knowns” via the process. Through this control, certain downstream attributes would be less inclined to wreak havoc.

• Water Quotes From U.S. Presidents

  I recently wrote an open letter to President Joe Biden requesting a commitment to make the funding of U.S. water infrastructure a priority in his Build Back Better program. I sent a similar open letter to president-elect Donald Trump back in 2016.

• Municipal Customer Feedback Spurs A More Economical Approach To Buried Meters

  McCrometer’s Dura Mag flow meter has gained a reputation as a robust tool for flow measurement within irrigation and other markets because of its accuracy and ruggedness while being an economical solution. Several technology limitations prevented the Dura Mag from widespread adoption in municipal water applications, but those issues are about to be addressed as McCrometer is preparing to launch the Dura Mag with expanded capabilities this year, enabling water utilities to take advantage of its benefits.

• The Trick To Managing Vertical Assets

  We get asked all the time; “Do you do vertical assets?”  I always respond with: “Of course we do, but what do you want to do with vertical assets?”  And that is where the discovery begins…

• PFAS: The Real Cost Of Inaction

  ALTRA Proven Solutions experts believe there are two key areas where they can have a positive impact in helping to eliminate PFAS from our environment: Advocacy and Innovation through ALTRA PFAS solutions.

• Choose The Right Cleanroom Insulation To Cut Hazardous Particulate Emission

  In this application note we consider the issues and describes a test protocol developed to measure the particulate contribution of three different types of insulation during typical cutting and fitting operations within a cleanroom.

• Surprise! “Checking The Box” Is Still An Option On The Federalwide Assurance (FWA)

  Historically, OHRP has said that the Common Rule reporting requirements apply to all nonexempt human subjects research covered by an FWA, regardless of funding source. In other words, institutions must follow the Common Rule reporting requirements for activities supported by a Common Rule department or agency, or for "check the box" research. Learn why it is critical for FWA-holding institutions to know whether the box is checked on their FWA and to understand what that means for research at their institution.

• Bioprocess Contaminant Detection Using Simple Western

  The identification and quantitation of process-related impurities during biotherapeutic development is critical to demonstrating the quality, efficacy and safety of the therapeutic agent. In this application note, we focus on the accurate detection of four candidate contaminants that may be present during various stages of the therapeutic protein and vaccine development processes: host cell protein (HCP), Protein A, green fluorescence protein (GFP) and bovine serum albumin (BSA).

• Durham, NC Improves Water Quality With Remote Pressure Monitoring, Sampling, And Flushing Stations

  The City of Durham is committed to providing safe drinking water to a service population of more than 289,000.  The City’s Department of Water Management (DWM) ensures the delivery of water to approximately 99,000 service connections through 1,400 miles of watermains. Lake Michie and Little River Reservoir are the two sources that deliver raw water to the City’s two treatment plants, using a combination of gravity flow and electric and hydro-powered pumping systems. Together, these plants have the combined treatment capacity of 64 million gallons per day (MGD) with an average demand is 28 MGD.

• Capitalizing On Evolving PFAS-Removal Options

  Granular activated carbon (GAC) and ion exchange (IX) resin have long histories in removing a variety of per- and polyfluoroalkyl substances (PFAS), known as ‘forever chemicals.’ But finding optimal treatment vessel and media efficiency depends on the specifics of the application. Here are some performance considerations of evolving options that can pay dividends for first-time and experienced PFAS removal operators alike.

• Tracking & Reporting Cellular Age Using Population Doubling Level & Not Cell Passage Number

  Here we explain explain how passage number and population doubling level are related and provide guidance and tools to help labs adopt the best practice of tracking PDL of cell cultures to help bring standardization to their own experimental protocols as well as to the field.

• On-Demand Webinar | How Software Solutions And The Infrastructure Bill Intersect

  Due to the Revised Lead and Copper Rule and the (eventual?) passing of the Infrastructure Investment and Jobs Act (IIJA), utilities are now required and incentivized to better assess and replace lead pipes within their networks.

• Why Ultrasonic Flow Metering Is Gaining Popularity Over Mechanical In Clean Water Applications

  Mechanical flow meters have always been a dependable option for drinking water treatment and distribution. However, the adoption of ultrasonic devices for these applications is growing steadily as water managers realize that advancements make them a better choice in many cases.

• Understanding Options Key To Selecting Most Effective, Lowest Cost PFAS Solution

  Municipal water utilities throughout the U.S. are increasingly grappling with the need to address PFAS once it is detected in source water. Because standards are a moving target while treatment options are limited and can represent a massive expense, addressing PFAS can be especially challenging for small water systems. The key to finding an optimal solution requires a thorough investigation of solutions.

• Water Quotes From Women

  As many of my followers know, I have been writing about the connection between women and water for a long time. Here is an excerpt from a post I wrote a number of years ago, A Valentine to Women Who Keep the Water Flowing…

• Identify & Define Your Cell Therapy’s Biomanufacturing Approach For Critical Process Parameters (CPPs)

  A consistent cell therapy manufacturing process entails a good scientific understanding of the process parameters in each unit operation and implementation of appropriate controls. That starts with identifying the CPPs in manufacturing.

• CGH: It’s More Than Hollywood

  Think holograms and some famous movies come to mind.  But the technology that makes those 3D images look so real is also used in everyday objects too, like credit cards, driver’s licenses, and plenty of security tools.

• Complimentary Techniques For Determining Relative Response Factor Of Non- Isolated Impurities

  The determination of the RRF, as it is carried out classically, requires a sample of the isolated impurity. It is possible to determine RRF of non-isolated impurities by using a combination of HPLC and Nuclear Magnetic Resonance (NMR).