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WHITE PAPERS AND CASE STUDIES

• Improving Enrollment With Better Data

  The industry hasn't realized the potential of information collected in clinical trials every day. Explore a solution that's changing how data is used to advance clinical trial recruitment and enrollment.

• Potential Fraud And Misconduct Investigated At Clinical Research Sites

  Uncover the truth of a for-cause investigation of potential misconduct and/or fraudulent activity on the part of senior management and investigators at one or more sites within a research organization.

• Cryobag Container Development For Cell & Gene Therapies

  ISR Reports addresses the logistical challenges faced by developers of cell and gene therapies regarding cold chain and cryopreservation.

• Speed To Market – API Large-Scale Commercial Manufacturing

  A pharmaceutical company was looking to partner with a CMO with commercial manufacturing capabilities, large-scale assets, multinational sites, and exemplary quality systems/U.S. FDA track record.

• Global Biotech Improves Clinical Trial Patient Recruitment With Digital Matching

  A global biotech initiated a phase III study for severe allergic asthma. Study protocol originally accounted for enrolling 222 patients across nine UK-based investigator sites. After deploying traditional recruitment methods, the sponsor only managed to randomize 20% of the target patient population in 11 months. By partnering with a solution provider they were able to get patient recruitment back on track and meet enrollment targets faster, which would not have been possible with a traditional recruitment approach.

• A Taste Masked And Easily Swallowed Malaria Drug For Elderly Patients

  Dysphagia impacts treatment compliance and disproportionately affects the elderly. Learn how microencapsulation enabled formulation of a water-soluble powder drives patient adherence.

• Streamline Cell Therapy Manufacturing With Rapid And Reliable Bead Removal

  Explore a Magnetic Separation System designed to enable closed, fully automated, and rapid cell isolation and bead removal, while decreasing variability in cell therapy manufacturing.

• Sulzer Dewatering Pumps Acclaimed By Pump Renter Neptune

  Neptune required a partner who can provide reliable technical innovations and proven solutions in wastewater and dewatering. Learn why they chose Sulzer as a partner in this collaboration.

• Cooling Tower Water Disinfection At Bielefeld, Germany

  The City of Bielefeld, Germany provides municipal utilities including electricity, natural gas, district heating, and water needs for a population of approximately 330,000. The municipality operates three gas-fired boilers with tapping turbines to feed into the district heating system that has a thermal peak load of 300 MW.

• Dechlorination Of Boiler Makeup Water At Baseload Generation Facility

  Atlantium Technologies installed a HOD UV system at a North American baseload generation facility to replace GAC filters and provide efficient and effective water treatment. The system ensures low chlorine concentration and reduces bacterial growth.

• Using A Fixed Bed Reactor System For Expansion Of Human Embryonic Stem Cells

  Regenerative medicine company ViaCyte Inc. explored new technologies to enable expanded scales of culturing hESCs for development of cell replacement therapies as a functional cure for Type 1 diabetes.

• Monoclor® Residual Control Manages Residual For Problematic 5.5 Million Gallon Tank For Eastern Municipal Water District

  Eastern Municipal Water District (EMWD) serves about 142,000 customers in Riverside County, California. The EMWD service area is one of the largest for any water district in arid southern California. On the drinking water side, EMWD manages two water treatment plants and over 15 reservoirs. With 70% of the district’s water coming from the Metropolitan Water District with chloramine disinfection, EMWD has become reliant on chloramine disinfection to manage long transmission lines and longer detention times due to on‐going water scarcity.